Cosmetics

Ingredient Safety Evaluation: Assessing the toxicological profile of cosmetic ingredients, including skin sensitization, irritation, phototoxicity, and systemic toxicity.

Exposure Assessment: Estimating the level of consumer exposure based on product usage patterns, routes of exposure (skin, inhalation, ingestion), and frequency of use.

Risk Characterization: Combining hazard data with exposure information to estimate the potential risks, including determining acceptable daily intake (ADI) or margin of safety (MoS) for ingredients.

Regulatory Compliance: Ensuring that cosmetic formulations meet national and international safety regulations (e.g., FDA, EU Cosmetics Regulation, ASEAN, etc.).

Toxicological Data Review: Reviewing existing toxicology studies, including in vitro and in vivo tests, and ensuring data reliability for safety assessments.

Carcinogenicity and Endocrine Disruption Evaluation: Evaluating the potential for ingredients to cause cancer or disrupt hormonal systems.

Safety of Preservatives and Fragrances: Assessing the risks posed by preservatives, fragrances, and other additives that may cause allergic reactions or sensitization.

Nanomaterial Risk Assessment: Evaluating the safety of nanoparticles used in cosmetics, such as titanium dioxide or zinc oxide, particularly for their potential to penetrate the skin.

Post-Market Surveillance: Monitoring adverse events and safety complaints related to cosmetic products to identify potential long-term risks.

Risk Communication: Reporting safety assessments and recommendations to regulatory bodies, product manufacturers, and the public to ensure transparency and safety.